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Tasmania's electricity connector to mainland, Basslink, goes into administration. For a recessive gene to actually manifest in an individual, both copies of the gene must be the recessive allele.
If an individual inherits only one recessive allele of the gene, the individual is considered a carrier who can pass on the potential for illness to their offspring. But when an individual inherits two copies of a dangerous recessive allele, the gene is said to be unmasked and he or she will inherit the condition. Trouble is, cousins share one set of grandparents.
So the risk of a child inheriting two copies of a dangerous allele is elevated compared to non-related marriages since they have a greater chance of inheriting the same recessive allele from their common ancestors. Nevertheless, British authorities determined that despite the increased risk, most children of cousin marriage are healthy. Privacy Policy Contact Us You may unsubscribe at any time by clicking on the provided link on any marketing message.
Bittles and M. Black tackled consanguineous marriage on a global scale in a paper in Annual Review of Anthropology. For the reasons discussed above, beyond just dangerous recessive alleles, the odds of a child of first cousins inheriting two copies of the same allele—any allele, whether recessive or not—is elevated.
Populations with fewer consanguineous marriages have higher heterozygosity, meaning individuals carry two different alleles for a given gene.
Unmasking is less common in highly heterozygous populations, so according to Bittles and Black, as cousin marriage declines, there should be corresponding increases in human health at a population level. The bottom line is that it is often safe to have children with your cousin, but doctors do recommend genetic counseling for prospective first cousin parents. In some cultures, it can be looked down upon for cousins to marry cousins. Many have rules and laws against incest close relatives marrying one another.
This is rooted in genetic concerns: close relatives who marry one another are more likely to have children with diseases or other issues. First cousins are considered to be close relatives while second cousins are not.
You may happen to know your second cousins as well. Family members who are more closely related to each other share more DNA. Similarly, your first cousin shares Genetic relationships between family members: Numbers indicate percentage of shared DNA between you and each relative Image from Wikimedia. Marriage between close relatives increases the chance of certain genetic concerns. Specifically, it increases the chances of having a child with a recessive condition.
You may remember from biology class that DNA is the instructional manual that tells our body how to grow, develop, and work properly. Genes are the individual units that make up our DNA. We all have two copies of every gene: one from mom and one from dad. Some variants are responsible for physical differences, such as hair or eye color. And some DNA variants cause diseases. Sometimes, having a variant in just one copy of a gene is enough to cause a disease.
But for recessive conditions, a person will only develop a disease when they have mutation in both copies of gene.
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