What is ttp illness

Sometimes it is associated with drugs the person is taking, an infection, bone marrow transplant, or pregnancy. Symptoms may be subtle and include fatigue, fever, headache, and diarrhea. As the condition progresses and clots form within blood vessels, platelets are consumed.

Bruising and bleeding from the mouth or gums may occur. Clots that form can disrupt the circulation. Patients may have high blood pressure, headaches, confusion, difficulty speaking and numbness. If anemia develops, symptoms may include fatigue, shortness of breath and heart palpitations. Plasma exchange is the most common treatment for TTP. How is Hemophilia Treated? Who is at Risk for Immune Thrombocytopenia? Who is at Risk of Iron-Deficiency Anemia?

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What Causes Thrombotic Thrombocytopenic Purpura? Triggers for Thrombotic Thrombocytopenic Purpura It's unclear what triggers inherited and acquired TTP, but some factors may play a role. These factors may include: Some diseases and conditions, such as pregnancy, cancer, HIV, lupus, and infections Some medical procedures, such as surgery and blood and marrow stem cell transplant Some medicines, such as chemotherapy, ticlopidine, clopidogrel, cyclosporine A, and hormone therapy and estrogens Quinine, which is a substance often found in tonic water and nutritional health products Source: National Heart, Lung, and Blood Institute, National Institutes of Health.

Brittonfield - East Syracuse, NY. Onondaga Hill - Syracuse, NY. Auburn, NY. Wellness Center - Camillus, NY. Thrombotic thrombocytopenic purpura. Accessed March 24, Thrombotic thrombocytopenic purpura and the hemolytic uremic syndromes. Hematology: Basic Principles and Practice. Review provided by VeriMed Healthcare Network. Editorial team. This condition also may be caused by: Cancer Chemotherapy Hematopoietic stem cell transplantation HIV infection Hormone replacement therapy and estrogens Medicines including ticlopidine, clopidogrel, quinine, and cyclosporine A.

Symptoms may include any of the following: Bleeding into the skin or mucus membranes Confusion Fatigue , weakness Fever Headache Pale skin color or yellowish skin color Shortness of breath Fast heart rate over beats per minute. Exams and Tests. The procedure is done as follows: First, you have your blood drawn as if donating blood.

As the blood is passed through a machine that separates blood into its different parts, the abnormal plasma is removed and your blood cells are saved.

Your blood cells are then combined with normal plasma from a donor, and then given back to you. This treatment is repeated daily until blood tests show improvement.

People who do not respond to this treatment or whose condition often returns may need to: Have surgery to remove their spleen Get medicines that suppress the immune system, such as steroids or rituximab.